A tissue-based approach to selection of reference genes for quantitative real-time PCR in a sheep osteoporosis model
Abstract Background In order to better understand the multifactorial nature of osteoporosis, animal models are utilized and compared to healthy controls.Female sheep are well established as a model for osteoporosis induced by ovariectomy, calcium and vitamin D low diet, application of steroids, or a combination of these treatments.Transcriptional s